{"id":490,"date":"2013-03-17T21:02:46","date_gmt":"2013-03-18T04:02:46","guid":{"rendered":"http:\/\/daryllafferty.com\/blog\/?p=490"},"modified":"2013-03-18T09:15:30","modified_gmt":"2013-03-18T16:15:30","slug":"nsaids","status":"publish","type":"post","link":"https:\/\/daryllafferty.com\/blog\/2013\/03\/17\/nsaids\/","title":{"rendered":"NSAIDS"},"content":{"rendered":"<p>Most of us occasionally take NSAIDs (Non Steroidal Anti-Inflammatory Drugs) such as Ibuprofen and Naproxen.  A recent study points out that some of these are safer to use than others.<br \/>\n<img decoding=\"async\" src=\" http:\/\/www.sciencebasedmedicine.org\/wp-content\/uploads\/2013\/03\/journal.pmed_.1001388.t001.png\" alt=\"Table\" width=500\/><br \/>\n(Right click on the image and select &#8220;View Image&#8221; to be able to read it)<\/p>\n<p>Of course acetaminophen (Tylenol) has even larger risks (it is reportedly the <a href=\"http:\/\/emedicine.medscape.com\/article\/820200-overview\" title=\"Acetaminophen Risks\">leading cause of liver transplants<\/a>)<\/p>\n<p>Over use of NSAIDs can increase the risk of heart attacks and strokes. From the table above, naproxen (Aleve) seems to be the safest (possibly even reducing risk), while ibuprofen (Advil) and celecoxib (Celebrex) are not bad.  One of the worst one seems to be rofecoxib (Vioxx), which has been removed from the market, and even worse is <a href=\"http:\/\/en.wikipedia.org\/wiki\/Diclofenac\" title=\"diclofenac\">diclofenac<\/a>, reportedly the most commonly prescribed NSAID in the world, sold under about 100 trade names, though it&#8217;s not common in the US.  From the table above it shows up to 100% increased risk of cardiovascular events.  <\/p>\n<p>Read <a href=\"http:\/\/www.sciencebasedmedicine.org\/index.php\/anti-inflammatory-drugs-a-closer-look-at-the-risks\/\" title=\"NSAIDs\">here<\/a> for a more detailed analysis and links to the original papers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Most of us occasionally take NSAIDs (Non Steroidal Anti-Inflammatory Drugs) such as Ibuprofen and Naproxen. A recent study points out that some of these are safer to use than others. (Right click on the image and select &#8220;View Image&#8221; to be able to read it) Of course acetaminophen (Tylenol) has even larger risks (it is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-490","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/posts\/490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/comments?post=490"}],"version-history":[{"count":8,"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/posts\/490\/revisions"}],"predecessor-version":[{"id":498,"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/posts\/490\/revisions\/498"}],"wp:attachment":[{"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/media?parent=490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/categories?post=490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/daryllafferty.com\/blog\/wp-json\/wp\/v2\/tags?post=490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}